Dog - Abortives

Why has my veterinary surgeon prescribed this medicine?

Various types of medication are used for pregnancy termination (abortion) in bitches. One type of medication (estradiol) needs to be given soon after mating to be effective, the other type of medication (algepristone) may be given up to 45 days after mating. However, side effects such as loss of appetite, fœtal expulsion, and swelling of the mammary glands may be seen at the time of abortion in bitches treated more than 20 days after mating.

A partial abortion may occur in 5% of bitches. Your veterinary surgeon may need to monitor your pet after treatment to check that the medication has worked and that pregnancy has been terminated.

Continual hormonal control of pregnancy may cause side effects in your pet. If your bitch is not intended for breeding, think about having your pet spayed (sterilised, neutered).

How do I give this medication?

  • Your veterinary surgeon will administer this medicine to your pet by injection.
  • A course of injections will be necessary.

Potential side effects

  • Side effects include temporary pain and swelling at the injection site.
  • Repeated use of these types of medication may result in an increased risk of your pet developing an infection in the uterus.
  • This medicine does not cause abortion in a small percentage of bitches.
  • After these types of medication your pet may come into season (heat) one to three months earlier than usual.
  • Other side effects may occur. If you notice anything unusual, contact your veterinary surgeon.

Possible drug interactions

  • Make sure to tell your veterinary surgeon what other medication you are giving to your pet.
  • Contact your veterinary surgeon if your pet experiences any unusual reactions when different medications are given together.

© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Created on Jun 24, 2008.

Brunswick Place Veterinary Clinic

Brunswick Place Veterinary Clinic is a trading name of CVS (UK) Limited; a company which owns over 500 veterinary practices and is registered in England and Wales. Registered number: 03777473. Registered office: CVS House, Owen Road, Diss, Norfolk IP22 4ER.

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