Cat & Dog - MGN-3
What is MGN-3?
MGN-3 is the trade name for arabinoxylan that has been extracted from the bran of rice and then enzymatically treated with an extract of shitake mushrooms. It is primarily used as an immune stimulant and to fight cancer in humans. It also appears to enhance outcomes achieved with conventional cancer treatments such as chemotherapy.
Why recommend administration of MGN-3 to my pet?
MGN-3 increases natural killer cell (an immune system cell) activity by stimulating increased levels of tumour necrosis factor and interferon (both natural substances made by the body that either prevent tumour cell replication or aid actual tumour cell death). Natural killer cells assist in identification and elimination of cells that have mutated and become cancerous. They also assist with immunity against infections in general.
Not surprisingly, then, MGN-3 has been investigated for and shown promise in humans for the treatment of HIV, cancer, and other alleged viral infections such as chronic fatigue immune deficiency syndrome (CFIDS). Not surprisingly, vets are likewise starting to explore the potential of MGN-3 in the treatment of cancer and viral infections in small animals. Investigations are still at a very early stage.
How successful is MGN-3?
Because investigations have only just begun, it is uncertain how effective MGN-3 potentially is to the treatment of small animal cancer and viral disorders. Given that the supplement appears safe and free of side effects, there appears little downside to exploring its use in veterinary medicine. Research to confirm or deny a benefit of MGN-3 in animals is greatly needed and completely lacking.
Where do I obtain MGN-3 and do I need a prescription?
You do not need a prescription to buy MGN-3. Please speak to one of the vets if you would like to discuss its use in your animal. We would be happy to advise.
© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Created on Jun 24, 2008.
